SIGNIFICANCE OF RETINAL VESSEL DIAMETERS IN THE ASSESSMENT OF OCULAR PERFUSION
G. E. Lang, W. Vilser, M. Tobis, Th. Riemer, A. Knittel, G. K. LangOcular perfusion and vascular dysfunction are of increasing significance in the diagnosis and treatment of ocular diseases.
Method: One important parameter for the assessment of ocular perfusion is the diameter of retinal vessels. With the Retinal Vessel Analyzer (RVA; Carl Zeiss Jena) the vessel diameters of retinal arteries and veins can be measured for the first time in vivo, non invasive, and documented automatically on line. With a special CCD-camera the retinal vessels are recorded. By PC a valid window is digitalised. The adaptive algorithms are independent of contrast and light intensity. The retinal vessel diameters are determined investigator independent.
Results: Der RVA is a valid and sensitive method, which allows to detect small vessel changes. Local and time dependent diameter changes, pulsations, vasomotion, blood pressure and respiratory dependent changes can be detected. Mechanisms of regulation and provocation can also be studied.
Conclusion: Knowledge about the physiology and pathophysiology of microcirculation is the basis for correct interpretation of retinal vessel behaviour conceming correct diagnosis and adequate therapy of vascular eye disesses.
Universitäts-Augenklinik, Prittwitzstr. 43, D-89075 Ulm
Supported by Carl Zeiss Jena