EFFECT OF RETINAL CRYOCOAGULATION ON THE RESORPTION OF DIABETIC VlTREOUS HEMORRHAGE PRELIMINARY RESULTS
P. Austermann, G. B. Kuba, C. Schade-Brittinger, J. Schmidt, P. Kroll
Retinal cryocoagulation as a therapy in vitreous hemorrhage due to diabetic retinopathy is discussed controversially. The present study was designed to examine the effect of retinal cryocoagulation on diabetic vitreous hemorrhage compared to its natural course.
Patients and methods: In a prospective, initial study, 20 patients with vitreous hemorrhage due to proliferative diabetic vitreoretinopathy (stage A) were randomized into two groups. Group l (6 males,4 females, medium age 65 years) was treated with retinal cryocoagulation. ln group 2 (4 males, 6 females, medium age 61 years) the natural course was observed. Both groups were examined again after 6 weeks. Visual acuity and severity of vitreous hemorrhage (indirect ophthalmoscopy) served as parameters.
Results: After six weeks, there was an increase in visual acuity in 7 patients (70%) in group 1, while 3 patients (30X) showed a constant visual acuity. Vitreous hemorrhage worsened in none of the patients, was stable in 2 patients, cleared partial in 6 patients and complete in 2 patients. In group 2 visual acuity remained constant in 9 patients (90%),only in one case (10%) there was an increase in visual acuity. Vitreous hemorrhage worsened in one of the patients , remained stable in 7 patients an cleared partial in 2 patients. Complete vitreous clearing was not observed.
Conclusion: The results suggest a positive effect of retinal cryocoagulation on the resorption of diabetic vitreous hemorrhage, compared to its natural course. In order to obtain statistical significance, a prospective study, according to the same design, is going on with 46 patients (power analysis with a = 5%, b = 20%).
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